Polycystic Ovary Syndrome in Medical Students: A Cross-Sectional Study of the Academic and Psychosocial Impact

<b>Background:</b> Polycystic Ovary Syndrome (PCOS) is a prevalent endocrine disorder affecting up to 13% of reproductive-aged females, often accompanied by physical, metabolic, and psychological challenges. Despite the demanding nature of medical education, limited research explores the burden of PCOS among medical students.<br /> <b>Objective:</b> To evaluate the academic, emotional, and psychosocial impact of PCOS on medical students across four U.S. medical schools.<br /> <b>Methods:</b> A cross-sectional survey was distributed to assigned female at birth medical students aged 18 and older. The questionnaire assessed PCOS diagnosis and treatment, academic performance, symptom burden, emotional well-being, and coping mechanisms. Descriptive statistics and Pearson correlation analyses were performed.<br /> <b>Results:</b> Of the 380 respondents (mean age 25.9), 30.3% reported a PCOS diagnosis—more than double the estimated global prevalence. PCOS was associated with academic stress (34.0%) and reduced work productivity due to emotional distress (70.2%). Symptom burden included menstrual irregularities, weight concerns, bloating, and acne. Emotional impacts were significant: 49.3% reported feeling unattractive, 50.7% worried about infertility, and 50.7% experienced self-blame. While many students demonstrated resilience and adopted positive coping strategies, a notable proportion reported emotional exhaustion and giving up efforts to manage the condition.<br /> <b>Conclusion:</b> Medical students with PCOS experience significant emotional and academic challenges, compounded by the rigors of their training. The prevalence and impact of PCOS in this population highlight the need for targeted institutional support, improved awareness, and mental health resources to promote student well-being and success.