Early diagnosis of breast cancer with a highly accurate dual-band graphene-based refractive index sensor

This study presents a precise refractive index (RI) sensor based on a dual-band graphene-based absorber for the early diagnosis of breast cancer. The sensor exhibits two strong absorption peaks at 4.58[Formula: see text]THz and 6.25[Formula: see text]THz, with efficiencies of 99.99% and 90%, respectively. Full-wave simulations and a transmission line model were used to assess the sensor’s performance, showing strong consistency. The sensor detects variations in the analyte’s RI, achieving a sensitivity of up to 2.22 THz/RIU and a Figure of Merit (FoM) of 7.7 RIU 1 . The use of a top-gate structure allows dynamic tuning of graphene’s chemical potential, enhancing adaptability. While the study is simulation-based and lacks experimental validation, it demonstrates the potential of this sensor for detecting biological changes, including those associated with breast cancer cells (RI range of 1.3 to 1.4). The simulation was performed using CST software with the FDTD solver. Future experimental validation will be necessary to confirm the device’s real-world applicability.

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Publication Details

Journal
Journal of Advanced Dielectrics
Published
2025-12-31
DOI
https://doi.org/10.1142/s2010135x25500407
Primary Topic
Plasmonic and Surface Plasmon Research
Type
article
Field-Weighted Citation Impact
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article

Early diagnosis of breast cancer with a highly accurate dual-band graphene-based refractive index sensor

Seyed Amin Khatami, Mohammad Danaie, Pejman Rezaei
Journal of Advanced Dielectrics
Plasmonic and Surface Plasmon Research
article

Early diagnosis of breast cancer with a highly accurate dual-band graphene-based refractive index sensor

Seyed Amin Khatami, Mohammad Danaie, Pejman Rezaei
article en

Abstract

This study presents a precise refractive index (RI) sensor based on a dual-band graphene-based absorber for the early diagnosis of breast cancer. The sensor exhibits two strong absorption peaks at 4.58[Formula: see text]THz and 6.25[Formula: see text]THz, with efficiencies of 99.99% and 90%, respectively. Full-wave simulations and a transmission line model were used to assess the sensor’s performance, showing strong consistency. The sensor detects variations in the analyte’s RI, achieving a sensitivity of up to 2.22 THz/RIU and a Figure of Merit (FoM) of 7.7 RIU 1 . The use of a top-gate structure allows dynamic tuning of graphene’s chemical potential, enhancing adaptability. While the study is simulation-based and lacks experimental validation, it demonstrates the potential of this sensor for detecting biological changes, including those associated with breast cancer cells (RI range of 1.3 to 1.4). The simulation was performed using CST software with the FDTD solver. Future experimental validation will be necessary to confirm the device’s real-world applicability.

Journal of Advanced Dielectrics
Semnan University (IR)
Good health and well-being
Openalex Percentile: Top 41%
Plasmonic and Surface Plasmon Research
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Early diagnosis of breast cancer with a highly accurate dual-band graphene-based refractive index sensor — Seyed Amin Khatami, Mohammad Danaie, et al. · Journal of Advanced Dielectrics (2025) | TGRS Research Map | TGRS