Optimizing Antiemetic Support in Anthracycline-Based Chemotherapy for Early Breast Cancer: Protocol for a Prospective Observational Study of Four-Drug Antiemetic Therapy Including Fosnetupitant and Olanzapine
This study will provide real-world evidence on the effectiveness and safety of a four-drug antiemetic regimen, including FosNTP and OLZ, in patients receiving anthracycline-based HEC and may inform optimal OLZ dosing strategies.
Authors
- Junji Kawasaki
- Eriko Tokunaga (ORCID: https://orcid.org/0000-0002-1640-5315)
- Mototsugu Shimokawa (ORCID: https://orcid.org/0000-0001-8140-4565)
- Sayuri Akiyoshi (ORCID: https://orcid.org/0000-0002-1237-5366)
- Ayako Higuchi
- Toshihiro Matsumoto
- Tomoaki Eto
- Hideki Ijichi
- Hiroaki Shimizu (ORCID: https://orcid.org/0000-0002-8550-4181)
- Wakako Tajiri (ORCID: https://orcid.org/0009-0005-8709-4031)
- Chinami Koga
- Yoshiaki Nakamura
- Yuka Maeda
- Yumiko Koi
Institutions
- Yamaguchi University (JP)
- National Hospital Organization Kyushu Cancer Center (JP)
- National Hospital Organization (JP)
- Keihin (Japan) (JP)
Publication Details
- Journal
- JMIR Research Protocols
- Published
- 2025-12-30
- DOI
- https://doi.org/10.2196/85648
- Primary Topic
- Nausea and vomiting management
- Type
- article
- Field-Weighted Citation Impact
- 0.00