The impact of NGF overexpression on proteome profile in WJ-MSC cultures
NGF overexpression enhances neurotrophin-related signaling but produces a sustained pro-apoptotic shift in WJ-MSC, suggesting limited benefit for cell survival. These findings require confirmation using functional apoptosis assays and in vivo models.
Authors
- Paulina Borkowska (ORCID: https://orcid.org/0000-0003-3150-3084)
- Monika Paul-Samojedny (ORCID: https://orcid.org/0000-0002-4685-1674)
- Magdalena B. Rother
- Dariusz Kuśmierz (ORCID: https://orcid.org/0000-0002-9028-3176)
- Malgorzata Kowalczyk
- Aleksandra Krawczyk
- Aleksandra Zielinska
Institutions
- Medical University of Silesia (PL)
- Leiden University Medical Center (NL)
Publication Details
- Journal
- Brain Research
- Published
- 2025-12-31
- DOI
- https://doi.org/10.1016/j.brainres.2025.150139
- Primary Topic
- Nerve injury and regeneration
- Type
- article
- Field-Weighted Citation Impact
- 0.00