Evaluating the Role of Analogies in Biochemistry Education: Lessons Learned From Pre‐ and Post‐Pandemic Dental Student Perceptions

Biochemistry forms the foundation for understanding biomolecules and molecular processes crucial to dental and oral biology. However, it is often perceived as a challenging subject for dental students with diverse educational backgrounds. Analogies are a pedagogical tool that helps explain new and abstract concepts in biochemistry. The COVID-19 pandemic significantly disrupted teaching and learning activities, prompting shifts in instructional models. This cross-sectional study evaluates dental students' perceptions of analogies in biochemistry education through surveys conducted at the National University of Singapore. Participants included pre-pandemic (2019) and post-pandemic (2024) dental student cohorts, consisting of 57 and 64 students, respectively. Both cohorts reported overwhelmingly positive responses toward the usefulness of analogies, with average scores of 4.6 ± 0.6 in 2019 and 4.7 ± 0.5 in 2024. Most students indicated that analogies enhanced their visualization of abstract concepts (100% in 2019 and 96.9% in 2024) and improved knowledge retention (82.5% in 2019 and 68.8% in 2024). However, a small proportion of students noted that analogies are taken literally and difficult to differentiate from reality (5.3% in 2019 and 4.7% in 2024). Students generally found analogies associated with unfamiliar topics to be more memorable. These findings suggest that analogies remain a relevant and effective tool in biochemistry education, even amid shifts in educational delivery models.