Molecular characterization and prognostic modeling of liquid- liquid phase separation-related genes in osteosarcoma based on single-cell sequencing and weighted gene co-expression network analysis
This study offers a novel framework for risk stratification in osteosarcoma, identifies seven novel LLPS-associated prognostic biomarkers, and presents valuable perspectives on the pathogenesis and potential therapeutic targets of osteosarcoma.
Authors
- Mingxiu Yang
- Liang Xiong (ORCID: https://orcid.org/0000-0002-2444-8243)
- Shanhang Li
- Xinyu Huang
- Min He (ORCID: https://orcid.org/0009-0006-2357-6266)
- Yangjie Cai (ORCID: https://orcid.org/0009-0001-2008-7727)
- Hening Li
- Zhuan Zou
- Yun Liu
- Jiaxing Zeng
Institutions
- Guangxi Medical University (CN)
- First Affiliated Hospital of GuangXi Medical University (CN)
Publication Details
- Journal
- Translational Cancer Research
- Published
- 2025-12-01
- DOI
- https://doi.org/10.21037/tcr-2025-1366
- Primary Topic
- Single-cell and spatial transcriptomics
- Type
- article
- Field-Weighted Citation Impact
- 0.00