Metastatic urothelial carcinoma of the urethra and glans penis with reported implantation via the urine: A case report

Urothelial carcinoma accounts for the vast majority of diagnosed bladder cancer cases. Urothelial carcinoma is prone to recurrence and metastasis despite complete resection of the lesions. The present case report describes a patient who underwent cystoprostatectomy due to a diagnosis of recurrent bladder cancer, with a penile lesion found several years after surgery. A partial penectomy was performed and the subsequent histopathology result showed urothelial carcinoma of the urethra and the epithelium of the glans and foreskin nested by micturition. The present case is an extremely rare incidence of the spread of cancer through the urine. To date, only a few such cases have been reported in the literature.

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Publication Details

Journal
Oncology Letters
Published
2025-12-31
DOI
https://doi.org/10.3892/ol.2025.15444
Primary Topic
Urinary and Genital Oncology Studies
Type
article
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article

Metastatic urothelial carcinoma of the urethra and glans penis with reported implantation via the urine: A case report

Olga Kuczkiewicz‐Siemion, Tomasz Demkow, Tomasz Kalinowski, Piotr Kalinowski et al.
Oncology Letters
Urinary and Genital Oncology Studies
article

Metastatic urothelial carcinoma of the urethra and glans penis with reported implantation via the urine: A case report

Olga Kuczkiewicz‐Siemion, Tomasz Demkow, Tomasz Kalinowski, Piotr Kalinowski, Beata Grochulska‑nalazek, Paweł Nalej, Roman Romaniuk
article en

Abstract

Urothelial carcinoma accounts for the vast majority of diagnosed bladder cancer cases. Urothelial carcinoma is prone to recurrence and metastasis despite complete resection of the lesions. The present case report describes a patient who underwent cystoprostatectomy due to a diagnosis of recurrent bladder cancer, with a penile lesion found several years after surgery. A partial penectomy was performed and the subsequent histopathology result showed urothelial carcinoma of the urethra and the epithelium of the glans and foreskin nested by micturition. The present case is an extremely rare incidence of the spread of cancer through the urine. To date, only a few such cases have been reported in the literature.

Oncology LettersVol. 31(2)
The Maria Sklodowska-Curie National Research Institute of Oncology (PL)
Good health and well-being
Openalex Percentile: Top 25%
Urinary and Genital Oncology Studies
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Metastatic urothelial carcinoma of the urethra and glans penis with reported implantation via the urine: A case report — Olga Kuczkiewicz‐Siemion, Tomasz Demkow, et al. · Oncology Letters (2025) | TGRS Research Map | TGRS