Apelin-13 attenuates microglia-mediated neuroinflammation following intracerebral hemorrhage via targeting JAK2/STAT3 signaling pathway

Apelin-13 attenuated brain injury after ICH by suppressing microglia-mediated neuroinflammation through APJ receptor-dependent inhibition of the JAK2/STAT3 pathway.

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Publication Details

Journal
Experimental Neurology
Published
2025-12-31
DOI
https://doi.org/10.1016/j.expneurol.2025.115633
Primary Topic
Apelin-related biomedical research
Type
article
Field-Weighted Citation Impact
0.00
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Apelin-13 attenuates microglia-mediated neuroinflammation following intracerebral hemorrhage via targeting JAK2/STAT3 signaling pathway

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Experimental Neurology
Apelin-related biomedical research
article

Apelin-13 attenuates microglia-mediated neuroinflammation following intracerebral hemorrhage via targeting JAK2/STAT3 signaling pathway

Pingping Guo, Xiangyu Zhang, Mengzhou Xue, V. Wee Yong, Jingjing Li, Yun Chen, Yang Liu, Huizhen Zhou, Qingli Wang
article en

Abstract

Apelin-13 attenuated brain injury after ICH by suppressing microglia-mediated neuroinflammation through APJ receptor-dependent inhibition of the JAK2/STAT3 pathway.

Experimental NeurologyVol. 398
Alberta Children's Hospital (CA), Second Affiliated Hospital of Zhengzhou University (CN)
Good health and well-being
Openalex Percentile: Top 29%
Apelin-related biomedical research
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