To assess malnutrition in continuous ambulatory peritoneal dialysis patients and its correlation with dose of continuous ambulatory peritoneal dialysis

Background: Malnutrition is a frequent and serious complication in patients undergoing continuous ambulatory peritoneal dialysis (CAPD), contributing significantly to morbidity and mortality. The malnutrition inflammation score (MIS) offers a comprehensive assessment by integrating clinical, anthropometric, and biochemical parameters. Aims and Objectives: The objective of this study was to evaluate the nutritional status of CAPD patients using the MIS and to determine its correlation with dialysis adequacy (Kt/V) and selected anthropometric and biochemical markers. Materials and Methods: A cross-sectional study was conducted among 30 CAPD patients at Maharani Laxmi Bai Medical College, Jhansi, from May 2024 to April 2025. Nutritional status was assessed using MIS, along with body mass index (BMI), mid-arm circumference (MAC), triceps skinfold thickness (TSF), and biochemical markers including serum albumin, hemoglobin, serum urea, creatinine, and total iron binding capacity (TIBC). Dialysis adequacy was calculated using weekly Kt/V. Statistical analysis was performed using Student’s t-test. Results: Among 30 participants (mean age 48.23 years, 60% male), 70% were malnourished (MIS ≥5). Malnourished patients exhibited significantly lower BMI, MAC, serum albumin, hemoglobin, and TIBC levels (P<0.05). Patients on higher-dose CAPD regimens (4 exchanges/day) demonstrated better dialysis adequacy (Kt/V = 1.43±0.10) and significantly lower MIS scores (P=0.001), suggesting improved nutritional outcomes with enhanced dialysis dosing. Conclusion: Malnutrition is prevalent among CAPD patients and closely correlates with lower anthropometric and biochemical indices. Higher dialysis adequacy is associated with better nutritional status. Routine MIS-based screening and individualized dialysis optimization are recommended to improve patient outcomes.