Comprehensive analysis of gene signature linking hypoxia and lactylation for predicting prognosis and immunotherapy response in patients with gastric cancer
This study uncovered the cellular heterogeneity of GC by integrating scRNA-seq and ST data. The results demonstrated that the HALRG risk model may be effective in predicting the clinical prognosis and has the potential to guide personalized treatment in GC.
Authors
- YuHan Wang
- X. Wang
- Ping Wang (ORCID: https://orcid.org/0000-0002-1653-5961)
- Rui Luo (ORCID: https://orcid.org/0000-0003-3555-5826)
- Ruiheng Xie
- Xian Zhou
- Xiaowei Tang
- Ruiyu Wang
- Ping Liu
Institutions
- Xuzhou Medical College (CN)
- Affiliated Hospital of Southwest Medical University (CN)
- Xuzhou Central Hospital (CN)
Publication Details
- Journal
- Translational Cancer Research
- Published
- 2025-12-01
- DOI
- https://doi.org/10.21037/tcr-2025-1453
- Primary Topic
- Ferroptosis and cancer prognosis
- Type
- article
- Field-Weighted Citation Impact
- 0.00