Silencing TMEM105 suppresses gastric cancer cell growth and migration via proliferation-associated pathways
High TMEM105 expression in GC is associated with poorer patient outcomes. It appears to influence cellular proliferation and contribute to the development and malignancy of gastric carcinoma. Consequently, TMEM105 could be a valuable therapeutic and prognostic target.
Authors
- Atefeh Zamani (ORCID: https://orcid.org/0000-0002-4674-6276)
- Behnoosh Nikonezhad
- Mobina Shahriarizade
Institutions
- Hamedan University of Medical Sciences (IR)
- Isfahan University of Medical Sciences (IR)
- Islamic Azad University, Science and Research Branch (IR)
- University of Isfahan (IR)
- Gene Therapy Laboratory (FR)
- Islamic Azad University of Shahrekord (IR)
- Biotechnology Research Institute (CN)
Publication Details
- Journal
- BMC Cancer
- Published
- 2025-12-30
- DOI
- https://doi.org/10.1186/s12885-025-15522-w
- Primary Topic
- Wnt/β-catenin signaling in development and cancer
- Type
- article
- Field-Weighted Citation Impact
- 0.00