MORELLA v2.2 - Machine learning Optimized Regression + ELLA - IOL Calculation Formula

MORELLA (Machine learning Optimized Regression + ELLA) is an innovative formula for calculating intraocular lens (IOL) power for cataract surgery. Developed using machine learning regression techniques applied to ocular biometric data. Key features:- 78 training cases validated against Barrett Universal II- 9 different A-Constants tested (117.7 - 119.4)- Axial length coverage: 19-34mm- R² = 99.61% (Basic model), R² = 99.88% (Complete model)- Mean Absolute Error: 0.31D (Basic), 0.15D (Complete) Author: BRUNO L. MIOLO MD M. ScVersion: 2.2Date: December 2024

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Publication Details

Journal
Zenodo (CERN European Organization for Nuclear Research)
Published
2025-12-30
DOI
https://doi.org/10.5281/zenodo.18099603
Primary Topic
Ophthalmology and Visual Impairment Studies
Type
article
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article

MORELLA v2.2 - Machine learning Optimized Regression + ELLA - IOL Calculation Formula

Bruno Luiz Miolo
Zenodo (CERN European Organization for Nuclear Research)
Ophthalmology and Visual Impairment Studies
article

MORELLA v2.2 - Machine learning Optimized Regression + ELLA - IOL Calculation Formula

Bruno Luiz Miolo
article en

Abstract

MORELLA (Machine learning Optimized Regression + ELLA) is an innovative formula for calculating intraocular lens (IOL) power for cataract surgery. Developed using machine learning regression techniques applied to ocular biometric data. Key features:- 78 training cases validated against Barrett Universal II- 9 different A-Constants tested (117.7 - 119.4)- Axial length coverage: 19-34mm- R² = 99.61% (Basic model), R² = 99.88% (Complete model)- Mean Absolute Error: 0.31D (Basic), 0.15D (Complete) Author: BRUNO L. MIOLO MD M. ScVersion: 2.2Date: December 2024

Zenodo (CERN European Organization for Nuclear Research)
Universidade Federal de São Paulo (BR)
Quality Education
Openalex Percentile: Top 29%
Ophthalmology and Visual Impairment Studies
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