18F-FDG, 18F-FP-CIT, and 18F-Florzolotau PET Imaging in Progressive Supranuclear Palsy

Patients with PSP exhibit metabolic deficits in cortical-subcortical networks, dopaminergic denervation in striatal-midbrain regions, and tau pathology localized to brainstem and thalamic areas. Tracer-specific SUVRs correlations revealed specific interplay among glucose hypometabolism, DAT deficiency, and tau accumulation.

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Publication Details

Journal
Clinical Nuclear Medicine
Published
2025-12-22
DOI
https://doi.org/10.1097/rlu.0000000000006254
Primary Topic
Parkinson's Disease Mechanisms and Treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

18F-FDG, 18F-FP-CIT, and 18F-Florzolotau PET Imaging in Progressive Supranuclear Palsy

Menglin Liang, Chenhao Jia, Q. Li, Zhaoxia Huang et al.
Clinical Nuclear Medicine
Parkinson's Disease Mechanisms and Treatments
article

18F-FDG, 18F-FP-CIT, and 18F-Florzolotau PET Imaging in Progressive Supranuclear Palsy

Menglin Liang, Chenhao Jia, Q. Li, Zhaoxia Huang, Ruixue Cui, Tzu-Chen Yen, Han Wang, Meiqi Wu, Tianhao Zhang
article en

Abstract

Patients with PSP exhibit metabolic deficits in cortical-subcortical networks, dopaminergic denervation in striatal-midbrain regions, and tau pathology localized to brainstem and thalamic areas. Tracer-specific SUVRs correlations revealed specific interplay among glucose hypometabolism, DAT deficiency, and tau accumulation.

Clinical Nuclear MedicineVol. 51(3)
Chinese Academy of Sciences (CN), Chinese Academy of Medical Sciences & Peking Union Medical College (CN), Peking Union Medical College Hospital (CN), University of Chinese Academy of Sciences (CN)
Openalex Percentile: Top 30%
Parkinson's Disease Mechanisms and Treatments
DOISourceOpenAlex
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