Impact of maternal diet on microbiota and health during pregnancy: a systematic review and correlational meta-analysis

This systematic review found that specific dietary components, particularly fiber, omega-3 fatty acids, and micronutrients, were associated with differences in maternal gut microbiota, with potential relevance to metabolic outcomes such as GDM, obesity, and hypertensive disorders of pregnancy. Meta-analysis results indicate that maternal health status significantly moderated the associations between dietary fat and protein intake and microbial taxa, suggesting that precision nutrition interventions warrant evaluation in metabolically at-risk populations. This study was registered at PROSPERO as CRD420251085137.

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Publication Details

Journal
American Journal of Clinical Nutrition
Published
2025-12-31
DOI
https://doi.org/10.1016/j.ajcnut.2025.101175
Primary Topic
Gut microbiota and health
Type
article
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Impact of maternal diet on microbiota and health during pregnancy: a systematic review and correlational meta-analysis

Marta Selma Royo, Eduard Flores Ventura, Sondra Turjeman, Sonia González, Maria Carmen Collado, Omry Koren
article en

Abstract

This systematic review found that specific dietary components, particularly fiber, omega-3 fatty acids, and micronutrients, were associated with differences in maternal gut microbiota, with potential relevance to metabolic outcomes such as GDM, obesity, and hypertensive disorders of pregnancy. Meta-analysis results indicate that maternal health status significantly moderated the associations between dietary fat and protein intake and microbial taxa, suggesting that precision nutrition interventions warrant evaluation in metabolically at-risk populations. This study was registered at PROSPERO as CRD420251085137.

American Journal of Clinical NutritionVol. 123(3)
Consejo Superior de Investigaciones Científicas (ES), Bar-Ilan University (IL), Universidad de Oviedo (ES), Instituto de Agroquímica y Tecnología de Alimentos (ES), Instituto de Investigación Sanitaria del Principado de Asturias (ES)
Zero hunger
Openalex Percentile: Top 35%
Gut microbiota and health
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