Association of Serum Sortilin and Insulin Resistance in Patients with Gestational Diabetes Mellitus.

This study aimed to evaluate serum sortilin level in individuals with GDM and to elucidate its relation with insulin resistance. In this study, we observed that serum sortilin concentration was significantly higher in individuals with gestational GDM than in healthy pregnant women. Also, serum sortilin had a statistically significant positive correlation with fasting blood glucose, fasting insulin, HOMA-IR, and glycated hemoglobin. The area under the curve of ROC and the Youden's index shows the impeccable diagnostic accuracy of sortilin.