Association between methylmalonic acid and Alpha-Klotho in American adults: A cross-sectional study
Our findings indicate a significant association between higher MMA levels and lower serum α-Klotho concentrations, It suggests that mitochondrial dysfunction may play a significant role in the aging process. Further research is necessary to validate these findings. This relationship warrants further investigation to clarify its implications for aging and health outcomes.
Authors
- Ronghui Bao
- Chang Zhou
- Rong Liu
- Qinqin Yu
- Hongyan Qi
- Lei Liao
- Jie Li
Institutions
- China Three Gorges University (CN)
- Yichang Central People's Hospital (CN)
Publication Details
- Journal
- PLoS ONE
- Published
- 2025-12-30
- DOI
- https://doi.org/10.1371/journal.pone.0337285
- Primary Topic
- Parathyroid Disorders and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00