Adjuvant chemoradiotherapy for stage III gastric cancer: A differential role in R0 and non-R0 resection

Adjuvant CCRT was associated with a trend toward improved survival in patients with non-R0 resection. However, it was not associated with additional survival benefits compared with chemotherapy in patients undergoing R0 resection after D2 lymphadenectomy, indicating that systemic therapy alone may be sufficient. These findings support the selective use of CCRT and underscore the need for prospective studies to optimize adjuvant strategies.

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Publication Details

Journal
Journal of the Chinese Medical Association
Published
2025-12-30
DOI
https://doi.org/10.1097/jcma.0000000000001332
Citations
1
Primary Topic
Gastric Cancer Management and Outcomes
Type
article
Field-Weighted Citation Impact
1.52
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article

Adjuvant chemoradiotherapy for stage III gastric cancer: A differential role in R0 and non-R0 resection

Nai-Jung Chiang, Ching-Yun Kung, Hung-Yuan Yu, Y. F. Chao et al.
1 citations
Journal of the Chinese Medical Association
Gastric Cancer Management and Outcomes
1.52
article

Adjuvant chemoradiotherapy for stage III gastric cancer: A differential role in R0 and non-R0 resection

Nai-Jung Chiang, Ching-Yun Kung, Hung-Yuan Yu, Y. F. Chao, Yin-Che Wang, Ming Huang Chen, I-Hsiang Lai, Ky Huang, Yi-Ping Hung, Anna Fen-Yau Li, Wen-Liang Fang, Shih-Chieh Lin
article en
1 citations

Abstract

Adjuvant CCRT was associated with a trend toward improved survival in patients with non-R0 resection. However, it was not associated with additional survival benefits compared with chemotherapy in patients undergoing R0 resection after D2 lymphadenectomy, indicating that systemic therapy alone may be sufficient. These findings support the selective use of CCRT and underscore the need for prospective studies to optimize adjuvant strategies.

Journal of the Chinese Medical AssociationVol. 89(2)
National Yang Ming Chiao Tung University (TW), Taipei Veterans General Hospital (TW), Taichung Veterans General Hospital (TW), Cheng Hsin General Hospital (TW)
Good health and well-being
Openalex Percentile: Top 12%
Gastric Cancer Management and Outcomes
1.52
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