Individuals with latent tuberculosis in a high TB endemic country show mild COVID-19
We observed that T cell reactivity to MTB was associated with milder COVID-19. Reduced severity of COVID-19 and higher OAS-1 gene expression in COVID-19 LTBi positive individuals suggest a protective effect in these individuals. Further studies are required to investigate the combined impact of MTB and SARS-CoV-2 infections in the host.
Authors
- Shama Qaiser
- Tulaib Iqbal
- Maliha Yameen
- Kiran Iqbal Masood (ORCID: https://orcid.org/0000-0002-5391-2834)
- Martin Rottenberg
- Bushra Jamil
- Zahra Abdulla Isa Yusuf Hasan
- Uzair Abbas
- Rabia Hussain
Institutions
- Aga Khan University (PK)
- Karolinska Institutet (SE)
- Dow University of Health Sciences (PK)
Publication Details
- Journal
- PLoS ONE
- Published
- 2025-12-30
- DOI
- https://doi.org/10.1371/journal.pone.0339240
- Citations
- 2
- Primary Topic
- Tuberculosis Research and Epidemiology
- Type
- article
- Field-Weighted Citation Impact
- 2.79