Clinical and Inflammatory Correlates of Negative Symptom Dimensions in Schizophrenia: Cross-Sectional Evidence for Neutrophil-to-Lymphocyte Ratio Associations With Motivational Deficits in Hospitalized Patients

In this inpatient cohort, NLR was the most consistent correlate of motivational negative symptoms, while CRP showed a weak association with Avolition, and C4 showed no clear relationship. Findings are hypothesis-generating and require replication in larger, longitudinal samples.

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Publication Details

Journal
Cureus
Published
2025-12-30
DOI
https://doi.org/10.7759/cureus.100390
Primary Topic
Tryptophan and brain disorders
Type
article
Field-Weighted Citation Impact
0.00
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article

Clinical and Inflammatory Correlates of Negative Symptom Dimensions in Schizophrenia: Cross-Sectional Evidence for Neutrophil-to-Lymphocyte Ratio Associations With Motivational Deficits in Hospitalized Patients

Cătălina Angela Crișan, I. Micluția, Octavia Căpățînă, Cosmin-Ioan Moga et al.
Cureus
Tryptophan and brain disorders
article

Clinical and Inflammatory Correlates of Negative Symptom Dimensions in Schizophrenia: Cross-Sectional Evidence for Neutrophil-to-Lymphocyte Ratio Associations With Motivational Deficits in Hospitalized Patients

Cătălina Angela Crișan, I. Micluția, Octavia Căpățînă, Cosmin-Ioan Moga, Mihaela Fadgyas Stanculete
article en

Abstract

In this inpatient cohort, NLR was the most consistent correlate of motivational negative symptoms, while CRP showed a weak association with Avolition, and C4 showed no clear relationship. Findings are hypothesis-generating and require replication in larger, longitudinal samples.

CureusVol. 17(12)
Iuliu Hațieganu University of Medicine and Pharmacy (RO)
Openalex Percentile: Top 46%
Tryptophan and brain disorders
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