Right-Sided Extravalvular Damage: An Overlooked Driver of Risk Model Failure in Low-Flow, Low-Gradient Aortic Stenosis
Markers of right-sided extravalvular damage conferred meaningful prognostic value in low-flow, low-gradient AS by correcting the STS-PROM score's tendency to overestimate post-TAVR mortality. The added value of these markers was most pronounced in moderate-risk patients, for whom existing tools appear least reliable. These markers may improve patient selection for TAVR and merit evaluation in other severe AS phenotypes.
Authors
- Annapoorna Kini (ORCID: https://orcid.org/0000-0002-7189-3307)
- Yash Prakash (ORCID: https://orcid.org/0000-0001-8593-327X)
- Ranbir Singh (ORCID: https://orcid.org/0009-0007-0279-5352)
- AKARSH SHARMA
- Eileen Galvani
- Oludamilola Akinmolayemi (ORCID: https://orcid.org/0000-0001-9813-9980)
- J. L. Halperin
- Lakshay Chopra
- Mihir Prakash
- Carlo M Mannina
- Samin K. Sharma
- Deepak L. Bhatt
- Stamatios Lerakis
Institutions
- Mount Sinai Hospital (US)
- Mount Sinai Hospital (US)
- Case Western Reserve University (US)
- Icahn School of Medicine at Mount Sinai (US)
Publication Details
- Journal
- Journal of the Society for Cardiovascular Angiography & Interventions
- Published
- 2025-12-30
- DOI
- https://doi.org/10.1016/j.jscai.2025.104116
- Primary Topic
- Cardiac Valve Diseases and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00