Why Physicians Delay in the Diagnosis and Treatment of Valproic Acid Toxicity

Early diagnosis of VA toxicity is necessary for timely, effective, high-quality care. Patients who initially received lactulose for hyperammonemia had slower recovery. Recognition of VA toxicity and prompt initiation of levocarnitine are associated with faster recovery and shorter LOS.

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Publication Details

Journal
Cureus
Published
2025-12-30
DOI
https://doi.org/10.7759/cureus.100436
Primary Topic
Pharmacological Effects and Toxicity Studies
Type
article
Field-Weighted Citation Impact
0.00
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article

Why Physicians Delay in the Diagnosis and Treatment of Valproic Acid Toxicity

Amber Asghar, Diane Levine, Muhammad Shahid
Cureus
Pharmacological Effects and Toxicity Studies
article

Why Physicians Delay in the Diagnosis and Treatment of Valproic Acid Toxicity

Amber Asghar, Diane Levine, Muhammad Shahid
article en

Abstract

Early diagnosis of VA toxicity is necessary for timely, effective, high-quality care. Patients who initially received lactulose for hyperammonemia had slower recovery. Recognition of VA toxicity and prompt initiation of levocarnitine are associated with faster recovery and shorter LOS.

CureusVol. 17(12)
Wayne State University (US), Wexham Park Hospital (GB), Detroit Medical Center (US)
Good health and well-being
Openalex Percentile: Top 17%
Pharmacological Effects and Toxicity Studies
DOIOpen Access PDFOpenAlex
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Why Physicians Delay in the Diagnosis and Treatment of Valproic Acid Toxicity — Amber Asghar, Diane Levine, et al. · Cureus (2025) | TGRS Research Map | TGRS