Diagnostic challenge of systemic amyloidosis mimicking EGFR-TKI toxicity in lung adenocarcinoma: a case report

When evaluating new symptoms in patients on targeted therapies, clinicians should not assume drug toxicity as the sole cause. A high index of suspicion for underlying systemic diseases, such as amyloidosis, is essential. Timely recognition and accurate diagnosis are critical to ensure appropriate and effective patient care.

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Publication Details

Journal
Translational Lung Cancer Research
Published
2025-12-01
DOI
https://doi.org/10.21037/tlcr-2025-913
Primary Topic
Amyloidosis: Diagnosis, Treatment, Outcomes
Type
article
Field-Weighted Citation Impact
0.00
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article

Diagnostic challenge of systemic amyloidosis mimicking EGFR-TKI toxicity in lung adenocarcinoma: a case report

Jooeun Lee, Min‐Kyung Yeo, H. D. Kang, Hyun Yi Kim et al.
Translational Lung Cancer Research
Amyloidosis: Diagnosis, Treatment, Outcomes
article

Diagnostic challenge of systemic amyloidosis mimicking EGFR-TKI toxicity in lung adenocarcinoma: a case report

Jooeun Lee, Min‐Kyung Yeo, H. D. Kang, Hyun Yi Kim, So-yun Kim, Chaeuk Chung
article en

Abstract

When evaluating new symptoms in patients on targeted therapies, clinicians should not assume drug toxicity as the sole cause. A high index of suspicion for underlying systemic diseases, such as amyloidosis, is essential. Timely recognition and accurate diagnosis are critical to ensure appropriate and effective patient care.

Translational Lung Cancer ResearchVol. 14(12)
Chungnam National University (KR), Chungnam National University Hospital (KR)
Good health and well-being
Openalex Percentile: Top 35%
Amyloidosis: Diagnosis, Treatment, Outcomes
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