Investigating the Effect of Coenzyme Q10 Supplementation on Cisplatin-Induced Nephrotoxicity in Patients Undergoing Chemotherapy: A Randomized Clinical Trial

The mean of BUN, blood creatinine, and GFR were not different between the two groups, before and after the intervention. The average creatinine levels increased after intervention between the mean of pre-intervention and post-intervention stages increased and GFR decreased; however, in the case of BUN, the opposite was not the case. This study's results can be used as a guide in drug administration for patients undergoing chemotherapy to reduce the renal side effects of prescribed drugs.

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Publication Details

Journal
Advanced Biomedical Research
Published
2025-12-01
DOI
https://doi.org/10.4103/abr.abr_81_23
Primary Topic
Chemotherapy-induced organ toxicity mitigation
Type
article
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article

Investigating the Effect of Coenzyme Q10 Supplementation on Cisplatin-Induced Nephrotoxicity in Patients Undergoing Chemotherapy: A Randomized Clinical Trial

Parisa Javadian, Amin Ahmadi, Ruhollah Masoumi, Mehrdad Sepehrni
Advanced Biomedical Research
Chemotherapy-induced organ toxicity mitigation
article

Investigating the Effect of Coenzyme Q10 Supplementation on Cisplatin-Induced Nephrotoxicity in Patients Undergoing Chemotherapy: A Randomized Clinical Trial

Parisa Javadian, Amin Ahmadi, Ruhollah Masoumi, Mehrdad Sepehrni
article en

Abstract

The mean of BUN, blood creatinine, and GFR were not different between the two groups, before and after the intervention. The average creatinine levels increased after intervention between the mean of pre-intervention and post-intervention stages increased and GFR decreased; however, in the case of BUN, the opposite was not the case. This study's results can be used as a guide in drug administration for patients undergoing chemotherapy to reduce the renal side effects of prescribed drugs.

Advanced Biomedical ResearchVol. 14(1)
Shahrekord University of Medical Sciences (IR)
Good health and well-being
Openalex Percentile: Top 29%
Chemotherapy-induced organ toxicity mitigation
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