Clinical and Treatment Profile of Late-Onset Bipolar Disorder: A Retrospective Evaluation

Aim: This study aims to compare the sociodemographic characteristics, clinical course, and treatment approaches of patients diagnosed with early-onset bipolar disorder (EOBD, 0.05), except for employment status (p=0.007). The EOBD group had a higher number of manic episodes (p=0.006). Lithium use was more frequent in LOBD patients, although not statistically significant (p=0.295), while olanzapine use was statistically significant (p=0.010). Antidepressant use was low in both groups (p=0.156). Conclusion: Late-onset bipolar disorder may present with distinct clinical features and treatment preferences compared to early-onset cases. Age at onset is a key determinant for clinical management and treatment planning.