Association of Matrix Metalloproteinase-11 Genotypes With Taiwan Gastric Cancer Risk and Clinical Features

While <i>MMP-11</i> polymorphisms are not suitable as population-level screening markers for GACA risk, rs738791 and rs28382575 may serve as predictors for metastasis, and rs28382575 and rs738792 as modifiers of gene-environment interaction. Functional validation is warranted to elucidate the biological relevance of these findings in GACA progression.

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Publication Details

Journal
Anticancer Research
Published
2025-12-30
DOI
https://doi.org/10.21873/anticanres.17931
Primary Topic
Protease and Inhibitor Mechanisms
Type
article
Field-Weighted Citation Impact
0.00

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article

Association of Matrix Metalloproteinase-11 Genotypes With Taiwan Gastric Cancer Risk and Clinical Features

Che-Lun Hsu, Hsu-Tung Lee, Te-Cheng Yueh, Chun-Kai Fu et al.
Anticancer Research
Protease and Inhibitor Mechanisms
article

Association of Matrix Metalloproteinase-11 Genotypes With Taiwan Gastric Cancer Risk and Clinical Features

Che-Lun Hsu, Hsu-Tung Lee, Te-Cheng Yueh, Chun-Kai Fu, MEI-CHIN MONG, TE-CHUN HSIA, MEI-DUE YANG, WEN-SHIN CHANG, DA-TIAN BAU, CHIA-WEN TSAI
article en

Abstract

While <i>MMP-11</i> polymorphisms are not suitable as population-level screening markers for GACA risk, rs738791 and rs28382575 may serve as predictors for metastasis, and rs28382575 and rs738792 as modifiers of gene-environment interaction. Functional validation is warranted to elucidate the biological relevance of these findings in GACA progression.

Anticancer ResearchVol. 46(1)
Asia University (TW), National Chung Hsing University (TW), China Medical University (TW), Taichung Veterans General Hospital (TW), China Medical University Hospital (TW), Taichung Armed Forces General Hospital (TW), National Defense Medical Center (TW)
China Medical University Hospital, Asia University, China Medical University
Good health and well-being
Openalex Percentile: Top 33%
Protease and Inhibitor Mechanisms
DOIOpen Access PDFOpenAlex
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