Impact of High Tacrolimus Exposure on Graft Function and Development of a Prediction Model in Kidney Transplant Recipients: A Single-Center Retrospective Cohort Study
Early high tacrolimus exposure is associated with impaired renal function and increased infection risk in the first year after transplantation. A prediction model incorporating genetic, inflammatory, and dosing factors could aid in early risk stratification.
Authors
- Rumin Liu
- Ping Zheng (ORCID: https://orcid.org/0000-0002-9088-1774)
- Juanhua Du
- Liqian Mo
- Wenli Zeng
- Renfei Xia
- Wenyu Yang
- Peijin Zhao
- Yilei Li
- Xin Luo
- Yan Chen
Institutions
- Nanfang Hospital (CN)
- Southern Medical University (CN)
Publication Details
- Journal
- Drug Design Development and Therapy
- Published
- 2025-12-01
- DOI
- https://doi.org/10.2147/dddt.s560652
- Primary Topic
- Renal Transplantation Outcomes and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Guangdong Provincial Hospital of Traditional Chinese Medicine
- Wu Jieping Medical Foundation