A Case Report of a Rare Subacute Cutaneous Lupus Erythematosus with Chin Prostration

Subacute cutaneous lupus erythematosus (SCLE) is a clinical subtype of cutaneous lupus erythematosus (CLE), an autoimmune connective tissue disease characterized by photosensitive rashes. This report presents a rare case of SCLE involving the chin. The patient presented with an annular, erythematous, scaling plaque on the left chin, which had been repeatedly misdiagnosed. Through integrated analysis of dermoscopic features, reflectance confocal microscopy (RCM) findings, and skin biopsy, a definitive diagnosis was established. Combination therapy with systemic corticosteroids and immunomodulators was initiated. Significant lesion regression was observed at the 19-week follow-up. The combined application of dermoscopy and RCM optimizes clinical management by reducing diagnostic errors and enabling real-time treatment monitoring.

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Publication Details

Journal
Clinical Cosmetic and Investigational Dermatology
Published
2025-12-01
DOI
https://doi.org/10.2147/ccid.s564703
Primary Topic
Systemic Lupus Erythematosus Research
Type
article
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article

A Case Report of a Rare Subacute Cutaneous Lupus Erythematosus with Chin Prostration

Jun Lu, Wanni Li, Weiwei Wu, Ping Wang et al.
Clinical Cosmetic and Investigational Dermatology
Systemic Lupus Erythematosus Research
article

A Case Report of a Rare Subacute Cutaneous Lupus Erythematosus with Chin Prostration

Jun Lu, Wanni Li, Weiwei Wu, Ping Wang, Yujia Liang, Chunxia Wang, Wen Luo
article en

Abstract

Subacute cutaneous lupus erythematosus (SCLE) is a clinical subtype of cutaneous lupus erythematosus (CLE), an autoimmune connective tissue disease characterized by photosensitive rashes. This report presents a rare case of SCLE involving the chin. The patient presented with an annular, erythematous, scaling plaque on the left chin, which had been repeatedly misdiagnosed. Through integrated analysis of dermoscopic features, reflectance confocal microscopy (RCM) findings, and skin biopsy, a definitive diagnosis was established. Combination therapy with systemic corticosteroids and immunomodulators was initiated. Significant lesion regression was observed at the 19-week follow-up. The combined application of dermoscopy and RCM optimizes clinical management by reducing diagnostic errors and enabling real-time treatment monitoring.

Clinical Cosmetic and Investigational DermatologyVol. Volume 18
Haikou City People's Hospital (CN), Hainan Medical University (CN)
Good health and well-being
Openalex Percentile: Top 27%
Systemic Lupus Erythematosus Research
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A Case Report of a Rare Subacute Cutaneous Lupus Erythematosus with Chin Prostration — Jun Lu, Wanni Li, et al. · Clinical Cosmetic and Investigational Dermatology (2025) | TGRS Research Map | TGRS