Distinct gut microbial profile in PIT1 lineage PitNETs: a potential link to cognitive impairment

These preliminary findings suggest that PIT1-lineage PitNETs may be associated with an increased susceptibility to cognitive impairment, potentially involving interactions between hormonal dysregulation and gut microbiota dysbiosis. This exploratory hypothesis provides a conceptual framework for future research to elucidate underlying mechanisms and explore potential interventions for cognitive impairment in PitNETs.

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Publication Details

Journal
Chinese Neurosurgical Journal
Published
2025-12-30
DOI
https://doi.org/10.1186/s41016-025-00421-7
Primary Topic
Gut microbiota and health
Type
article
Field-Weighted Citation Impact
0.00

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article

Distinct gut microbial profile in PIT1 lineage PitNETs: a potential link to cognitive impairment

Junjun Li, Lingye Zhang, Chen Ma, Xingli Deng et al.
Chinese Neurosurgical Journal
Gut microbiota and health
article

Distinct gut microbial profile in PIT1 lineage PitNETs: a potential link to cognitive impairment

Junjun Li, Lingye Zhang, Chen Ma, Xingli Deng, Jiang Long, Jinpeng Lv
article en

Abstract

These preliminary findings suggest that PIT1-lineage PitNETs may be associated with an increased susceptibility to cognitive impairment, potentially involving interactions between hormonal dysregulation and gut microbiota dysbiosis. This exploratory hypothesis provides a conceptual framework for future research to elucidate underlying mechanisms and explore potential interventions for cognitive impairment in PitNETs.

Chinese Neurosurgical JournalVol. 11(1)
Kunming Medical University (CN), Ningxia Hui Autonomous Region Peoples Hospital (CN), First Affiliated Hospital of Kunming Medical University (CN), Puer University (CN)
Kunming Medical University, Yunnan University
Good health and well-being
Openalex Percentile: Top 35%
Gut microbiota and health
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