<scp>FOLFOX</scp> Versus <scp>FOLFIRI</scp> as Second‐Line Chemotherapy in Patients With Advanced Biliary Tract Cancers: A Multicenter, Italian Study
FOLFOX and FOLFIRI showed modest, comparable efficacy as second-line regimens in patients with BTC pretreated with cisplatin-gemcitabine, with platinum-sensitive patients experiencing significantly longer PFS and OS, independently of the chosen second-line regimen.
Authors
- Eleonora Gusmaroli
- Filippo de Braud (ORCID: https://orcid.org/0000-0003-0103-730X)
- Caterina Vivaldi (ORCID: https://orcid.org/0000-0001-9307-2326)
- Sara Lonardi (ORCID: https://orcid.org/0000-0002-7593-8138)
- Monica Niger
- Vincenzo Mazzaferro (ORCID: https://orcid.org/0000-0002-4013-8085)
- Chiara Pircher (ORCID: https://orcid.org/0000-0001-8173-824X)
- Federico Nichetti (ORCID: https://orcid.org/0000-0001-8044-4207)
- Maria Bensi (ORCID: https://orcid.org/0000-0002-5647-0525)
- Silvia Bozzarelli (ORCID: https://orcid.org/0000-0002-8118-7342)
- G. Trovato (ORCID: https://orcid.org/0009-0004-9526-0725)
- Carolina Sciortino
- S. Sperotto
- Giacomo Di Paolo
- Rita Balsano
- Simone Rota (ORCID: https://orcid.org/0000-0002-6839-1488)
- Filippo Pietrantonio
- Lisa Salvatore
- Francesca Salani
- Mario Domenico Rizzato
- Virginia Genovesi
- Michele Droz Dit Busset
- Silvia Marchesi
- Lorenza Rimassa
Institutions
- Università Cattolica del Sacro Cuore (IT)
- University of Pisa (IT)
- Humanitas University (IT)
- University of Padua (IT)
- Scuola Superiore Sant'Anna (IT)
- University of Milan (IT)
- Agostino Gemelli University Polyclinic (IT)
- Istituto Oncologico Veneto (IT)
- Fondazione IRCCS Istituto Nazionale dei Tumori (IT)
- IRCCS Humanitas Research Hospital (IT)
- Azienda Ospedaliera Universitaria Pisana (IT)
Publication Details
- Journal
- Liver International
- Published
- 2025-12-30
- DOI
- https://doi.org/10.1111/liv.70502
- Primary Topic
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00