DACT1 inhibits cuproptosis and promotes cell malignancy via activation of PI3K/AKT signaling in laryngeal squamous cell carcinoma

DACT1 promotes the malignant behavior of LSCC cells and suppresses cuproptosis by activating the PI3K/AKT signaling.

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Publication Details

Journal
European journal of medical research
Published
2025-12-30
DOI
https://doi.org/10.1186/s40001-025-03662-5
Primary Topic
PI3K/AKT/mTOR signaling in cancer
Type
article
Field-Weighted Citation Impact
0.00
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article

DACT1 inhibits cuproptosis and promotes cell malignancy via activation of PI3K/AKT signaling in laryngeal squamous cell carcinoma

J. Jillian Zhang, Linli Tian, Jingchun Ge, Yan Guo et al.
European journal of medical research
PI3K/AKT/mTOR signaling in cancer
article

DACT1 inhibits cuproptosis and promotes cell malignancy via activation of PI3K/AKT signaling in laryngeal squamous cell carcinoma

J. Jillian Zhang, Linli Tian, Jingchun Ge, Yan Guo, Liang Li, Ming Liu
article en

Abstract

DACT1 promotes the malignant behavior of LSCC cells and suppresses cuproptosis by activating the PI3K/AKT signaling.

European journal of medical researchVol. 31(1)
Harbin Medical University (CN), Second Affiliated Hospital of Harbin Medical University (CN), First Affiliated Hospital of Harbin Medical University (CN)
Good health and well-being
Openalex Percentile: Top 35%
PI3K/AKT/mTOR signaling in cancer
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