Outcomes of Hematopoietic Stem Cell Transplantation Following the Use of Blinatumomab in Pediatric Relapsed B-Cell Acute Lymphoblastic Leukemia: A Single-Center Experience
In this single-center experience from a low-/middle-income country (LMIC), blinatumomab served as an effective bridge to HSCT, enabling MRD-negative remissions with favorable post-transplant outcomes. Viral reactivations and steroid-refractory GVHD were reported, underlining the need for robust surveillance. Broader access to blinatumomab and prospective studies are needed to validate these findings and to evaluate cost-effectiveness in LMICs.
Authors
- Anukriti Srivastava
- Hari Gaire (ORCID: https://orcid.org/0000-0002-7685-6345)
- Nita Radhakrishnan
- Sudipto Bhattacharya (ORCID: https://orcid.org/0000-0001-6215-7204)
- Aditi Tulsiyan
- Anuj Singh
Institutions
- Institute of Child Health (IN)
- Institute of Cytology and Preventive Oncology (IN)
Publication Details
- Journal
- Journal of Hematology
- Published
- 2025-12-01
- DOI
- https://doi.org/10.14740/jh2132
- Primary Topic
- Acute Lymphoblastic Leukemia research
- Type
- article
- Field-Weighted Citation Impact
- 0.00