Protopanaxadiol Induces Apoptosis in NPC/HK1 Human Nasopharyngeal Carcinoma Cells <i>via</i> the Fas/Caspase-8 Signaling Pathway

Protopanaxadiol selectively suppresses NPC/HK1 growth, induces apoptotic markers, and promotes apoptosis via the Fas/caspase-8 signaling pathway. These findings provide foundational evidence that protopanaxadiol is a promising candidate to improve NPC therapy.

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Publication Details

Journal
Anticancer Research
Published
2025-12-30
DOI
https://doi.org/10.21873/anticanres.17934
Citations
1
Primary Topic
Ginseng Biological Effects and Applications
Type
article
Field-Weighted Citation Impact
0.81
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article

Protopanaxadiol Induces Apoptosis in NPC/HK1 Human Nasopharyngeal Carcinoma Cells via the Fas/Caspase-8 Signaling Pathway

Yaw-Chang Huang, Yuyan Lan, Y.C. Siew, CHIH-CHUN WANG et al.
1 citations
Anticancer Research
Ginseng Biological Effects and Applications
0.81
article

Protopanaxadiol Induces Apoptosis in NPC/HK1 Human Nasopharyngeal Carcinoma Cells via the Fas/Caspase-8 Signaling Pathway

Yaw-Chang Huang, Yuyan Lan, Y.C. Siew, CHIH-CHUN WANG, YUN-CHI TSAI, CHUANCHIEN YANG, YINGXIAO LI
article en
1 citations

Abstract

Protopanaxadiol selectively suppresses NPC/HK1 growth, induces apoptotic markers, and promotes apoptosis via the Fas/caspase-8 signaling pathway. These findings provide foundational evidence that protopanaxadiol is a promising candidate to improve NPC therapy.

Anticancer ResearchVol. 46(1)
E-Da Hospital (TW), Hualien Tzu Chi Medical Center (TW), I-Shou University (TW)
Good health and well-being
Openalex Percentile: Top 20%
Ginseng Biological Effects and Applications
0.81
DOISourceOpenAlex
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