Lack of S100A8 Impairs Lung-Protective Immunity Against <i>Streptococcus pneumoniae</i>
Deletion of S100A8 disturbs lung-protective immunity against S pneumoniae in mice. At the same time, analysis of the S100A8/A9 protein complex in clinical samples may help to distinguish patients with bacterial vs viral pneumonia.
Authors
- Philippe Tessier
- Konstantin Neumann (ORCID: https://orcid.org/0000-0002-5527-2834)
- Konrad Peukert (ORCID: https://orcid.org/0000-0002-0516-3314)
- Lara-Kristin Steinmetz
- Christian Bode (ORCID: https://orcid.org/0000-0002-0830-870X)
- Benjamin Seeliger (ORCID: https://orcid.org/0000-0001-7373-752X)
- Ulrich A. Maus (ORCID: https://orcid.org/0000-0002-6172-8746)
- Jennifer Stolper
- K Brand
- Lena Ostermann
- A Pich
- Carolin Flasche
- Regina Maus
- Johannes Roth
- Thomas Vogl
Institutions
- University of Münster (DE)
- University Hospital Bonn (DE)
- Medizinische Hochschule Hannover (DE)
- University Hospital Münster (DE)
- German Center for Infection Research (DE)
- German Centre for Cardiovascular Research (DE)
- German Center for Lung Research (DE)
- Université Laval (CA)
- FH Münster University of Applied Sciences (DE)
Publication Details
- Journal
- The Journal of Infectious Diseases
- Published
- 2025-12-24
- DOI
- https://doi.org/10.1093/infdis/jiaf647
- Primary Topic
- S100 Proteins and Annexins
- Type
- article
- Field-Weighted Citation Impact
- 0.00