Penile papulonecrotic tuberculid in a 30-year-old male: A rare manifestation of cutaneous tuberculosis

Papulonecrotic tuberculid (PNT) is a rare cutaneous manifestation of tuberculosis (TB), believed to result from a hypersensitivity reaction to Mycobacterium tuberculosis antigens in individuals with a robust immune response. While it typically presents as necrotizing papules on the extremities or trunk, genital involvement, particularly of the penis, is exceedingly rare and often misdiagnosed. We report a case of a 30-year-old immunocompetent male with asymptomatic necrotic papules on the glans penis. A strongly positive Mantoux test (19 mm induration) and histopathological features consistent with PNT, along with a complete therapeutic response to anti-tubercular therapy (ATT), confirmed the diagnosis. This case underscores the importance of considering tuberculids in the differential diagnosis of penile lesions, especially in TB-endemic regions.

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Journal
Journal of Skin and Sexually Transmitted Diseases
Published
2025-12-30
DOI
https://doi.org/10.25259/jsstd_127_2025
Primary Topic
Infectious Diseases and Tuberculosis
Type
article
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article

Penile papulonecrotic tuberculid in a 30-year-old male: A rare manifestation of cutaneous tuberculosis

Sonia Sabhandasani, Amit Shivaji Kerure, Balkrishana Pralhadrao Nikam
Journal of Skin and Sexually Transmitted Diseases
Infectious Diseases and Tuberculosis
article

Penile papulonecrotic tuberculid in a 30-year-old male: A rare manifestation of cutaneous tuberculosis

Sonia Sabhandasani, Amit Shivaji Kerure, Balkrishana Pralhadrao Nikam
article en

Abstract

Papulonecrotic tuberculid (PNT) is a rare cutaneous manifestation of tuberculosis (TB), believed to result from a hypersensitivity reaction to Mycobacterium tuberculosis antigens in individuals with a robust immune response. While it typically presents as necrotizing papules on the extremities or trunk, genital involvement, particularly of the penis, is exceedingly rare and often misdiagnosed. We report a case of a 30-year-old immunocompetent male with asymptomatic necrotic papules on the glans penis. A strongly positive Mantoux test (19 mm induration) and histopathological features consistent with PNT, along with a complete therapeutic response to anti-tubercular therapy (ATT), confirmed the diagnosis. This case underscores the importance of considering tuberculids in the differential diagnosis of penile lesions, especially in TB-endemic regions.

Journal of Skin and Sexually Transmitted DiseasesVol. 7
Krishna Institute of Medical Sciences (IN), Pain Clinic of India (IN), Advanced Centre for Treatment, Research and Education in Cancer (IN)
Good health and well-being
Openalex Percentile: Top 25%
Infectious Diseases and Tuberculosis
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Penile papulonecrotic tuberculid in a 30-year-old male: A rare manifestation of cutaneous tuberculosis — Sonia Sabhandasani, Amit Shivaji Kerure, et al. · Journal of Skin and Sexually Transmitted Diseases (2025) | TGRS Research Map | TGRS