Traumatic Optic Neuropathy After Head Trauma: Pathophysiology, Interventions, and Evidence From Meta‐Analysis

This systematic review and meta-analysis provides indicative evidence that early surgical decompression may offer superior outcomes compared with corticosteroid therapy, especially for indirect injuries. Specifically, this meta-analysis suggests that surgical intervention may offer superior outcomes without increasing adverse events. Nevertheless, the evidence base remains limited, and these results should be interpreted with caution. While corticosteroids alone show limited benefit and may be considered adjunctive when surgery is not feasible, high-quality multicenter randomized trials are urgently needed to standardize treatment protocols and optimize patient outcomes.

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Publication Details

Journal
ANZ Journal of Surgery
Published
2025-12-30
DOI
https://doi.org/10.1111/ans.70454
Primary Topic
Facial Trauma and Fracture Management
Type
article
Field-Weighted Citation Impact
0.00
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article

Traumatic Optic Neuropathy After Head Trauma: Pathophysiology, Interventions, and Evidence From Meta‐Analysis

Shu Min Tang, Y. Xu, Xiaosu Wu, Cui Huang
ANZ Journal of Surgery
Facial Trauma and Fracture Management
article

Traumatic Optic Neuropathy After Head Trauma: Pathophysiology, Interventions, and Evidence From Meta‐Analysis

Shu Min Tang, Y. Xu, Xiaosu Wu, Cui Huang
article en

Abstract

This systematic review and meta-analysis provides indicative evidence that early surgical decompression may offer superior outcomes compared with corticosteroid therapy, especially for indirect injuries. Specifically, this meta-analysis suggests that surgical intervention may offer superior outcomes without increasing adverse events. Nevertheless, the evidence base remains limited, and these results should be interpreted with caution. While corticosteroids alone show limited benefit and may be considered adjunctive when surgery is not feasible, high-quality multicenter randomized trials are urgently needed to standardize treatment protocols and optimize patient outcomes.

ANZ Journal of Surgery
Chongqing Emergency Medical Center (CN)
Good health and well-being
Openalex Percentile: Top 25%
Facial Trauma and Fracture Management
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