Successful systemic phage therapy for implant-associated MRSA spondylodiscitis
This case demonstrates the potential role of systemic bacteriophage therapy as a safe and effective treatment option for deep-seated, antibiotic-refractory MRSA infections. It also provides a practical framework for regulatory approval and clinical use of individualized phage therapy in complex infectious diseases.
Authors
- Ondřej Beran (ORCID: https://orcid.org/0000-0001-8861-1794)
- T. Belšán (ORCID: https://orcid.org/0000-0003-1808-9704)
- Simona Arientová (ORCID: https://orcid.org/0000-0003-4621-930X)
- Michal Holub
Institutions
- Military University Hospital Prague (CZ)
Publication Details
- Journal
- International Journal of Infectious Diseases
- Published
- 2025-12-30
- DOI
- https://doi.org/10.1016/j.ijid.2025.108357
- Primary Topic
- Bacteriophages and microbial interactions
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Ministerstvo Obrany České Republiky