ECG Never Lies: A Case of Apical Hypertrophic Cardiomyopathy

Apical hypertrophic cardiomyopathy (ApHCM) is a less common variant of hypertrophic cardiomyopathy, characterized by predominant thickening of the left ventricular apex. We describe a 64-year-old man presenting with dyspnea and T-wave inversions in the lateral precordial leads. Although initial echocardiography was reported as normal, further imaging revealed an "ace of spades" configuration on ventriculography and an anechoic apical area on off-axis views. Contrast echocardiography confirmed apical wall thickening with systolic obliteration. Cardiac magnetic resonance imaging showed patchy late gadolinium enhancement, and Holter monitoring excluded sustained arrhythmias. This case highlights the role of multimodality imaging in ApHCM.

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Publication Details

Journal
Journal of Cardiovascular Echography
Published
2025-10-01
DOI
https://doi.org/10.4103/jcecho.jcecho_54_25
Primary Topic
Cardiomyopathy and Myosin Studies
Type
article
Field-Weighted Citation Impact
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article

ECG Never Lies: A Case of Apical Hypertrophic Cardiomyopathy

Ilaria Minnucci, Francesco Briani
Journal of Cardiovascular Echography
Cardiomyopathy and Myosin Studies
article

ECG Never Lies: A Case of Apical Hypertrophic Cardiomyopathy

Ilaria Minnucci, Francesco Briani
article en

Abstract

Apical hypertrophic cardiomyopathy (ApHCM) is a less common variant of hypertrophic cardiomyopathy, characterized by predominant thickening of the left ventricular apex. We describe a 64-year-old man presenting with dyspnea and T-wave inversions in the lateral precordial leads. Although initial echocardiography was reported as normal, further imaging revealed an "ace of spades" configuration on ventriculography and an anechoic apical area on off-axis views. Contrast echocardiography confirmed apical wall thickening with systolic obliteration. Cardiac magnetic resonance imaging showed patchy late gadolinium enhancement, and Holter monitoring excluded sustained arrhythmias. This case highlights the role of multimodality imaging in ApHCM.

Journal of Cardiovascular EchographyVol. 35(4)
University of Verona (IT)
Openalex Percentile: Top 30%
Cardiomyopathy and Myosin Studies
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