Prehospital Tranexamic Acid Combined with Blood Transfusion Reduced the Short-Term Mortality Risk in Trauma Patients at Risk for Hemorrhage

Prehospital TXA combined with transfusion significantly improves short-term survival and reduces organ failure in bleeding trauma patients, without increasing thromboembolic risk. These findings support early integration of TXA into prehospital transfusion protocols.

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Publication Details

Journal
Therapeutics and Clinical Risk Management
Published
2025-12-01
DOI
https://doi.org/10.2147/tcrm.s564232
Primary Topic
Trauma, Hemostasis, Coagulopathy, Resuscitation
Type
article
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0.00
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article

Prehospital Tranexamic Acid Combined with Blood Transfusion Reduced the Short-Term Mortality Risk in Trauma Patients at Risk for Hemorrhage

Bining Yang, Zheng Qian
Therapeutics and Clinical Risk Management
Trauma, Hemostasis, Coagulopathy, Resuscitation
article

Prehospital Tranexamic Acid Combined with Blood Transfusion Reduced the Short-Term Mortality Risk in Trauma Patients at Risk for Hemorrhage

Bining Yang, Zheng Qian
article en

Abstract

Prehospital TXA combined with transfusion significantly improves short-term survival and reduces organ failure in bleeding trauma patients, without increasing thromboembolic risk. These findings support early integration of TXA into prehospital transfusion protocols.

Therapeutics and Clinical Risk ManagementVol. Volume 21
Soochow University (CN), Second Affiliated Hospital of Soochow University (CN)
Good health and well-being
Openalex Percentile: Top 31%
Trauma, Hemostasis, Coagulopathy, Resuscitation
DOIOpen Access PDFOpenAlex
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Prehospital Tranexamic Acid Combined with Blood Transfusion Reduced the Short-Term Mortality Risk in Trauma Patients at Risk for Hemorrhage — Bining Yang, Zheng Qian · Therapeutics and Clinical Risk Management (2025) | TGRS Research Map | TGRS