Modeling Normal Tissue Complication Probability of Radiation-Induced Alopecia Following Intensity-Modulated Radiation Therapy in Glioblastoma Patients

Multivariate logistic regression, integrating dosimetric and clinical factors, offers enhanced predictive accuracy for RIA compared to the LKB model. These findings emphasize the importance of optimizing IMRT plans to limit scalp dose and considering chemotherapy in risk stratification. Implementation of these models may improve patient-centered care by balancing tumor control and toxicity reduction.