Postinfectious cerebellitis in a preadolescent child

Varicella is a common, typically self-limiting, viral illness that often occurs in childhood. However, neurological complications, such as encephalitis, vasculopathy and cerebellitis, can occur. Postinfectious cerebellitis is presumed to be immune-mediated, typically presenting within days to weeks of rash onset. Diagnosis is primarily clinical, as early neuroimaging and cerebrospinal fluid (CSF) analysis may be normal. Treatment is usually supportive, though corticosteroids or antivirals may be used in severe or atypical cases.We report a case of postinfectious cerebellitis in a preadolescent male, presenting 1 week after the resolution of varicella rash. Symptoms included ataxia, dysarthria, dysdiadochokinesia and hypertonia. Despite classic cerebellar signs, imaging and CSF analysis were unremarkable. Clinical improvement followed a short course of empirical treatment for suspected meningoencephalitis; however, residual neurological deficits persisted, necessitating physiotherapy.This case highlights the potential for significant neurological involvement in postinfectious cerebellitis despite normal investigations, underscoring the need for clinical vigilance, timely intervention and multidisciplinary follow-up.

Authors

Institutions

Publication Details

Journal
BMJ Case Reports
Published
2025-12-01
DOI
https://doi.org/10.1136/bcr-2025-268087
Primary Topic
Autoimmune Neurological Disorders and Treatments
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Postinfectious cerebellitis in a preadolescent child

Weihong Zhao, Violet Alavi, Syed Sherazi
BMJ Case Reports
Autoimmune Neurological Disorders and Treatments
article

Postinfectious cerebellitis in a preadolescent child

Weihong Zhao, Violet Alavi, Syed Sherazi
article en

Abstract

Varicella is a common, typically self-limiting, viral illness that often occurs in childhood. However, neurological complications, such as encephalitis, vasculopathy and cerebellitis, can occur. Postinfectious cerebellitis is presumed to be immune-mediated, typically presenting within days to weeks of rash onset. Diagnosis is primarily clinical, as early neuroimaging and cerebrospinal fluid (CSF) analysis may be normal. Treatment is usually supportive, though corticosteroids or antivirals may be used in severe or atypical cases.We report a case of postinfectious cerebellitis in a preadolescent male, presenting 1 week after the resolution of varicella rash. Symptoms included ataxia, dysarthria, dysdiadochokinesia and hypertonia. Despite classic cerebellar signs, imaging and CSF analysis were unremarkable. Clinical improvement followed a short course of empirical treatment for suspected meningoencephalitis; however, residual neurological deficits persisted, necessitating physiotherapy.This case highlights the potential for significant neurological involvement in postinfectious cerebellitis despite normal investigations, underscoring the need for clinical vigilance, timely intervention and multidisciplinary follow-up.

BMJ Case ReportsVol. 18(12)
Wrightington, Wigan and Leigh NHS Foundation Trust (GB)
Good health and well-being
Openalex Percentile: Top 30%
Autoimmune Neurological Disorders and Treatments
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.

Postinfectious cerebellitis in a preadolescent child — Weihong Zhao, Violet Alavi, et al. · BMJ Case Reports (2025) | TGRS Research Map | TGRS