Feasibility of Low-Pass Whole Genome Sequencing for Detecting Somatic Copy Number Alterations in Formalin-Fixed Uveal Melanoma Specimens

The successful application of LP-WGS to FFPE uveal melanoma specimens supports prospective investigations in rare cancers and may enable the development of personalized treatment strategies.

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Publication Details

Journal
Translational Vision Science & Technology
Published
2025-12-30
DOI
https://doi.org/10.1167/tvst.14.12.31
Primary Topic
Ocular Oncology and Treatments
Type
article
Field-Weighted Citation Impact
0.00

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article

Feasibility of Low-Pass Whole Genome Sequencing for Detecting Somatic Copy Number Alterations in Formalin-Fixed Uveal Melanoma Specimens

Ren-Chin Wu, An-Ning Chao, Angel Chao, Yun-Shien Lee et al.
Translational Vision Science & Technology
Ocular Oncology and Treatments
article

Feasibility of Low-Pass Whole Genome Sequencing for Detecting Somatic Copy Number Alterations in Formalin-Fixed Uveal Melanoma Specimens

Ren-Chin Wu, An-Ning Chao, Angel Chao, Yun-Shien Lee, Chiao-Yun Lin, Chen-Yang Huang
article en

Abstract

The successful application of LP-WGS to FFPE uveal melanoma specimens supports prospective investigations in rare cancers and may enable the development of personalized treatment strategies.

Translational Vision Science & TechnologyVol. 14(12)
Chang Gung University (TW), Ming Chuan University (TW), Linkou Chang Gung Memorial Hospital (TW)
Chang Gung Medical Foundation
Good health and well-being
Openalex Percentile: Top 28%
Ocular Oncology and Treatments
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