Mirtazapine or ondansetron for hyperemesis gravidarum: a randomized placebo-controlled trial
The trial showed reduced Pregnancy Unique Quantification of Emesis 24 score in the mirtazapine group compared with the placebo group among pregnant people with hyperemesis gravidarum. Ondansetron resulted in a smaller reduction in Pregnancy Unique Quantification of Emesis 24 score that did not reach statistical significance.
Authors
- Christina Lindegaard Poulsen
- Andreas Kryger Jensen (ORCID: https://orcid.org/0000-0002-8233-9176)
- Tina Bergmann Futtrup
- Marjoes Droogh
- Astrid Collatz Schyum
- Benny Kirschner
- Line Markdanner Lindgren
- Tine Wrønding (ORCID: https://orcid.org/0009-0008-9670-7241)
- K. Fogh
- J. A. Andersen
- Ellen Christine Leth Løkkegaard
- Ture Lange Nielsen
- Hanne Brix Westergaard
- Anne Ostenfeld
- Lars Henning Pedersen
- Emma Louise Kaderly Rasmussen
- Sara Kjeldgaard Lange
- Rebecca Debess
- Sif Emilie Carlsen
- Paul Vignir Axelsson Bryde
- Tonny Studsgaard Petersen
- Jens Dalsgaard
- Terese Faurschou Nielsen
Institutions
- University of Copenhagen (DK)
- Frederiksberg Hospital (DK)
- Herlev Hospital (DK)
- Aarhus University Hospital (DK)
- Copenhagen University Hospital (DK)
Publication Details
- Journal
- American Journal of Obstetrics and Gynecology
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1016/j.ajog.2025.12.061
- Primary Topic
- Pregnancy and Medication Impact
- Type
- article
- Field-Weighted Citation Impact
- 0.00