A lactylation-driven prognostic model for lung adenocarcinoma: cellular lactylation heterogeneity and immune insights

This study presents a lactylation-based prognostic model for LUAD and uncovers potential immune-related mechanisms by which highly lactylated epithelial cells may contribute to immune evasion and tumor progression.

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Publication Details

Journal
Translational Lung Cancer Research
Published
2025-12-01
DOI
https://doi.org/10.21037/tlcr-2025-aw-1170
Primary Topic
Immune cells in cancer
Type
article
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article

A lactylation-driven prognostic model for lung adenocarcinoma: cellular lactylation heterogeneity and immune insights

Ziheng Yang, Fan Li, Bo Zhao, Sheng Zhang et al.
Translational Lung Cancer Research
Immune cells in cancer
article

A lactylation-driven prognostic model for lung adenocarcinoma: cellular lactylation heterogeneity and immune insights

Ziheng Yang, Fan Li, Bo Zhao, Sheng Zhang, Hui Cheng
article en

Abstract

This study presents a lactylation-based prognostic model for LUAD and uncovers potential immune-related mechanisms by which highly lactylated epithelial cells may contribute to immune evasion and tumor progression.

Translational Lung Cancer ResearchVol. 14(12)
Tongji Hospital (CN), Huazhong University of Science and Technology (CN)
Good health and well-being
Openalex Percentile: Top 35%
Immune cells in cancer
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