Imbalances in circulating monocyte and high-density lipoprotein cholesterol exacerbates the residual risk of incident myocardial infarction beyond LDL-C: a real-life, prospective cohort study
Chronic imbalances in monocyte and HDL-C levels are significantly associated with incident MI among individuals with low LDL-C levels. Longitudinally tracing MHR changes and targeting elevated MHR may help to optimize risk assessment and management of MI.
Authors
- Yulong Lan (ORCID: https://orcid.org/0000-0002-6143-9709)
- Lois Balmer (ORCID: https://orcid.org/0000-0001-5618-0555)
- Youren Chen
- Wei Wang
- Xingang Li
- Dan Wu
- Shouling Wu
- Xiong Ding
Institutions
- Edith Cowan University (AU)
- Capital Medical University (CN)
- Shantou University (CN)
- Wuhan University (CN)
- Kailuan General Hospital (CN)
- First Affiliated Hospital of Shantou University Medical College (CN)
- Second Affiliated Hospital of Shantou University Medical College (CN)
- Shandong First Medical University (CN)
Publication Details
- Journal
- Journal of Translational Medicine
- Published
- 2025-12-30
- DOI
- https://doi.org/10.1186/s12967-025-07028-7
- Citations
- 1
- Primary Topic
- Inflammatory Biomarkers in Disease Prognosis
- Type
- article
- Field-Weighted Citation Impact
- 1.05
Funders
- Guangdong Medical Research Foundation