Validity of fatty acid profiling in saliva: A comparative analysis with blood-based matrices

Despite the small sample size and exploratory nature of the study, our findings support that salivary FAs may only partially reflect blood FA profiles, with substantial interindividual variability. Larger and more comprehensive studies are needed to confirm these preliminary results and clarify the conditions under which saliva could become a feasible alternative matrix.

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Publication Details

Journal
Nutrition
Published
2025-12-30
DOI
https://doi.org/10.1016/j.nut.2025.113086
Primary Topic
Salivary Gland Disorders and Functions
Type
article
Field-Weighted Citation Impact
0.00
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article

Validity of fatty acid profiling in saliva: A comparative analysis with blood-based matrices

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Validity of fatty acid profiling in saliva: A comparative analysis with blood-based matrices

C.V. Agostoni, G.M. Tartaglia, S. Bettocchi, N. Cenzato, A. Comotti, C. Bertoni, M. Abodi, S. Turolo, A. Mazzocchi, M.L. Syren, G.P. Milani
article en

Abstract

Despite the small sample size and exploratory nature of the study, our findings support that salivary FAs may only partially reflect blood FA profiles, with substantial interindividual variability. Larger and more comprehensive studies are needed to confirm these preliminary results and clarify the conditions under which saliva could become a feasible alternative matrix.

NutritionVol. 145
University of Milan (IT), Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico (IT), Ospedale Maggiore (IT)
Zero hunger
Openalex Percentile: Top 32%
Salivary Gland Disorders and Functions
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