Importance of Frozen Section in the Accurate Diagnosis of a Space Occupying Lesion in a 59 Year Old Female Patient - A Case Report

Follicular thyroid carcinoma is a well-differentiated form of thyroid cancer that primarily spreads through the bloodstream to distant organs such as the lungs, brain, and lymph nodes. Although distant metastases in follicular thyroid carcinoma are relatively common to these sites, metastasis to the skull is uncommon, its incidence being 2.5–5.8%. Furthermore, their clinical presentation as a brain tumour is a very rare clinical scenario, it’s an incidence being 1%. This case report of a 55-year-old female presenting with occipital headache highlights the importance of considering thyroid carcinoma in the differential diagnosis when evaluating space-occupying lesions (SOLs) of the brain. A frozen section proved to be diagnostic, which showed numerous follicles invading into the bone. A subsequent FNAC of the thyroid confirmed the diagnosis. This case also highlights the importance of recognizing atypical presentations of thyroid carcinoma, which need to be kept in mind for appropriate diagnosis and optimum treatment, and, hence, avoiding exhaustive complicated procedures.

Authors

Institutions

Publication Details

Journal
Medical Journal of Dr D Y Patil Vidyapeeth
Published
2025-12-01
DOI
https://doi.org/10.4103/mjdrdypu.mjdrdypu_1070_24
Primary Topic
Thyroid Cancer Diagnosis and Treatment
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Importance of Frozen Section in the Accurate Diagnosis of a Space Occupying Lesion in a 59 Year Old Female Patient - A Case Report

Prasant Chandra, Mayur Ambekar, Ashish Chugh, Charusheela Gore et al.
Medical Journal of Dr D Y Patil Vidyapeeth
Thyroid Cancer Diagnosis and Treatment
article

Importance of Frozen Section in the Accurate Diagnosis of a Space Occupying Lesion in a 59 Year Old Female Patient - A Case Report

Prasant Chandra, Mayur Ambekar, Ashish Chugh, Charusheela Gore, Arpana Dharwadkar, Rhushvi Thakkar
article en

Abstract

Follicular thyroid carcinoma is a well-differentiated form of thyroid cancer that primarily spreads through the bloodstream to distant organs such as the lungs, brain, and lymph nodes. Although distant metastases in follicular thyroid carcinoma are relatively common to these sites, metastasis to the skull is uncommon, its incidence being 2.5–5.8%. Furthermore, their clinical presentation as a brain tumour is a very rare clinical scenario, it’s an incidence being 1%. This case report of a 55-year-old female presenting with occipital headache highlights the importance of considering thyroid carcinoma in the differential diagnosis when evaluating space-occupying lesions (SOLs) of the brain. A frozen section proved to be diagnostic, which showed numerous follicles invading into the bone. A subsequent FNAC of the thyroid confirmed the diagnosis. This case also highlights the importance of recognizing atypical presentations of thyroid carcinoma, which need to be kept in mind for appropriate diagnosis and optimum treatment, and, hence, avoiding exhaustive complicated procedures.

Medical Journal of Dr D Y Patil VidyapeethVol. 18(Suppl 2)
Dr. D. Y. Patil Medical College, Hospital and Research Centre (IN), Dr. D.Y. Patil Vidyapeeth, Pune (IN)
Gender equality
Openalex Percentile: Top 29%
Thyroid Cancer Diagnosis and Treatment
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.

Importance of Frozen Section in the Accurate Diagnosis of a Space Occupying Lesion in a 59 Year Old Female Patient - A Case Report — Prasant Chandra, Mayur Ambekar, et al. · Medical Journal of Dr D Y Patil Vidyapeeth (2025) | TGRS Research Map | TGRS