Obituary: Nobel Laureate James Dewey Watson (1928–2025)

Dear Editor, James Dewey Watson, one of the most influential figures in modern biology, passed away on November 6, 2025, at the age of 97 years. His life’s work changed the direction of science and gave humanity a deeper understanding of how living beings inherit their traits. Born in Chicago on April 6, 1928, he grew up as a bright and curious child. He developed an early love for reading and learning, which shaped his entire career. He entered university at a young age and soon discovered his interest in genetics. After completing his doctoral studies, he moved to Europe, where he met many young scientists working to solve the great mysteries of life. Watson’s most important contribution came in 1953 when, along with Francis Crick, he proposed the double-helix structure of DNA. This simple yet elegant model explained how genetic information is stored and passed on from one generation to the next. Their discovery laid the foundation for modern genetics, biotechnology, gene therapy, and much of today’s medical research. The work earned him the Nobel Prize, and it is still considered one of the greatest scientific breakthroughs of the twentieth century. Apart from research, Watson played a major role in shaping scientific institutions. He taught generations of students, encouraged young researchers, and contributed to the early stages of the human genome project. His leadership helped create spaces where scientists could work together and make faster progress in understanding human biology. However, Watson’s journey was not without controversy. In his later years, some of his public comments on race and intelligence were widely criticized for being insensitive and scientifically unsupported. Many people felt that these remarks overshadowed his achievements. Therefore, his life stands as a reminder that great scientific talent must also be accompanied by responsibility and respect for all human beings. Even with his complicated legacy, there is no doubt that Watson’s scientific contributions transformed the world. The shape of DNA that students learn today in every biology classroom traces back to his early work. Medicines, genetic tests, and many modern technologies owe something to the discovery he helped make more than 70 years ago. As we reflect on his life, we remember James Dewey Watson as a brilliant, determined, and sometimes controversial figure who changed the story of science forever. His work continues to guide researchers, inspire students, and illuminate the endless curiosity that drives human progress. Financial support and sponsorship Nil. Conflicts of interest There are no conflicts of interest.