Revisiting Scurvy: Unveiling a Forgotten Disease

Scurvy, a disease of Vitamin C deficiency, was once a major health concern, particularly among sailors and explorers. Although considered a rare condition in modern times, scurvy is a significant health issue, particularly among vulnerable populations such as children with global developmental delay, autism spectrum disorder, and physical disabilities. Clinical manifestations of scurvy include fatigue, malaise, musculoskeletal pain, as well as cutaneous signs such as perifollicular petechiae and ecchymoses. Here, we are presenting a case of 12-year-old male child with cerebral palsy, with purpuric lesions on his extremities and painful swelling on his foot. Dermoscopy showed follicular hyperkeratosis, coiled hairs, and perifollicular petechiae. Lab investigations revealed microcytic hypochromic anemia. X-rays of bilateral knees showed Frankel’s sign and Wimberger’s ring sign. A skin biopsy confirmed a follicular hyperkeratotic plug with perifollicular inflammation and extravasation of red blood cells. The patient was treated with oral ascorbic acid, leading to significant clinical improvement.

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Publication Details

Journal
Indian Journal of Paediatric Dermatology
Published
2025-10-01
DOI
https://doi.org/10.4103/ijpd.ijpd_36_25
Primary Topic
Vitamin C and Antioxidants Research
Type
article
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article

Revisiting Scurvy: Unveiling a Forgotten Disease

KETKI S. CHAVANDA, Ajay Ovhal, Krishna Girdhar Kalantri, Bhushan A. Darkase
Indian Journal of Paediatric Dermatology
Vitamin C and Antioxidants Research
article

Revisiting Scurvy: Unveiling a Forgotten Disease

KETKI S. CHAVANDA, Ajay Ovhal, Krishna Girdhar Kalantri, Bhushan A. Darkase
article en

Abstract

Scurvy, a disease of Vitamin C deficiency, was once a major health concern, particularly among sailors and explorers. Although considered a rare condition in modern times, scurvy is a significant health issue, particularly among vulnerable populations such as children with global developmental delay, autism spectrum disorder, and physical disabilities. Clinical manifestations of scurvy include fatigue, malaise, musculoskeletal pain, as well as cutaneous signs such as perifollicular petechiae and ecchymoses. Here, we are presenting a case of 12-year-old male child with cerebral palsy, with purpuric lesions on his extremities and painful swelling on his foot. Dermoscopy showed follicular hyperkeratosis, coiled hairs, and perifollicular petechiae. Lab investigations revealed microcytic hypochromic anemia. X-rays of bilateral knees showed Frankel’s sign and Wimberger’s ring sign. A skin biopsy confirmed a follicular hyperkeratotic plug with perifollicular inflammation and extravasation of red blood cells. The patient was treated with oral ascorbic acid, leading to significant clinical improvement.

Indian Journal of Paediatric DermatologyVol. 26(4)
Government Medical College (IN)
No poverty
Openalex Percentile: Top 34%
Vitamin C and Antioxidants Research
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