Asymptomatic osteolysis as a risk factor for cardiovascular disease after total hip arthroplasty: A retrospective cohort study

We found no association between periacetabular osteolysis and possible risk markers for CVD. There was a trend towards higher incidence of CVD among patients with periacetabular osteolysis. Based on the results from our relatively small cohort it cannot be excluded that low-grade peri-implant inflammation may increase long term risk of CVD following THA.

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Publication Details

Journal
PLoS ONE
Published
2025-12-30
DOI
https://doi.org/10.1371/journal.pone.0338676
Primary Topic
Orthopaedic implants and arthroplasty
Type
article
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article

Asymptomatic osteolysis as a risk factor for cardiovascular disease after total hip arthroplasty: A retrospective cohort study

Sara Aspberg, Michael Axenhus, Evaldas Laurenčikas, Olof Sköldenberg et al.
PLoS ONE
Orthopaedic implants and arthroplasty
article

Asymptomatic osteolysis as a risk factor for cardiovascular disease after total hip arthroplasty: A retrospective cohort study

Sara Aspberg, Michael Axenhus, Evaldas Laurenčikas, Olof Sköldenberg, Nils P. Hailer, Thomas Eisler, Agata Rysinska, Max Gordon, Daniel Hallman
article en

Abstract

We found no association between periacetabular osteolysis and possible risk markers for CVD. There was a trend towards higher incidence of CVD among patients with periacetabular osteolysis. Based on the results from our relatively small cohort it cannot be excluded that low-grade peri-implant inflammation may increase long term risk of CVD following THA.

PLoS ONEVol. 20(12)
Uppsala University Hospital (SE), Danderyds sjukhus (SE), Karolinska Institutet (SE), Glanrhyd Hospital (GB), Södertälje Sjukhus (SE), The Swedish Hip Arthroplasty Register (SE)
Good health and well-being
Openalex Percentile: Top 25%
Orthopaedic implants and arthroplasty
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