Six-Year Trends in ICU Admission, Management, and Outcomes of Chimeric Antigen Receptor T-Cell Patients in the ICU

ICU admission rates after CAR T-cell treatment are declining. Although ICU patients are older with higher severity of illness and toxicity grades, ICU mortality after CAR T-cell therapy remains low.

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Publication Details

Journal
Critical Care Medicine
Published
2025-12-30
DOI
https://doi.org/10.1097/ccm.0000000000007000
Primary Topic
CAR-T cell therapy research
Type
article
Field-Weighted Citation Impact
0.00
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article

Six-Year Trends in ICU Admission, Management, and Outcomes of Chimeric Antigen Receptor T-Cell Patients in the ICU

L. Feng, Brian T. Hill, Prabalini Rajendram, Jason R. Westin et al.
Critical Care Medicine
CAR-T cell therapy research
article

Six-Year Trends in ICU Admission, Management, and Outcomes of Chimeric Antigen Receptor T-Cell Patients in the ICU

L. Feng, Brian T. Hill, Prabalini Rajendram, Jason R. Westin, Ananda Dharshan, Stephen M. Pastores, Alice Gallo de Moraes, Simon Mucha, Natalie Kostelecky, Megan M. Herr, Melissa Beasley, Agrima Mian, Colleen McEvoy, Heather P. May, Cristina Gutiérrez, Elena Mead, Safa Mohamed Yousif Ahmed, Matthew K. Hensley, Sikemi Ibikunle, Yi Lin, Anne Rain T. Brown, Arsal Tharwani, and the Chimeric Antigen Receptor for the ICU (CAR-ICU) Initiative, Joseph L. Nates, R. Scott Stephens
article en

Abstract

ICU admission rates after CAR T-cell treatment are declining. Although ICU patients are older with higher severity of illness and toxicity grades, ICU mortality after CAR T-cell therapy remains low.

Critical Care MedicineVol. 54(3)
Roswell Park Comprehensive Cancer Center (US), Apple (Israel) (IL), Cleveland Clinic (US), Mayo Clinic (US), Memorial Sloan Kettering Cancer Center (US), The University of Texas MD Anderson Cancer Center (US), Johns Hopkins University (US), Washington University in St. Louis (US), Cornell University (US), Johns Hopkins Medicine (US), Mayo Clinic in Arizona (US), Pittsburg State University (US)
Good health and well-being
Openalex Percentile: Top 30%
CAR-T cell therapy research
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